How's your womb's enviroment?
Did you know that the events surrounding a baby girl's birth may affect the age at which she later goes through menopause?
(Getty Images)
Researchers found that exposure in the womb to the man-made estrogen, diethylstilbestrol (DES), as well as certain characteristics of the mom, had small effects on the timing of this natural biological process.

"These aren't drastic changes, but the fact that something at birth can affect something 50 years later is fascinating," Dr. Anne Steiner of the University of North Carolina at Chapel Hill told Reuters Health.

A woman's ovaries hold the most eggs while she is in her mother's womb: about 5 million at 24 weeks gestation. By birth, she's left with roughly 2 million. The count continues to fall until menopause, when the last 1,000 eggs of her supply begin to run out and menstruation and fertility end.

This knowledge led Steiner and her colleagues to wonder if the womb might be a susceptible time period for women. Could things about her mom, the environment or the birth itself affect how many eggs a girl has when she's born? And might this subsequently alter her age at menopause?

According to the National Institute on Aging, 51 is the average age at which a woman reaches menopause (has her last period). But some women have their last period in their 40s and some have it later in their 50s.

About half of the women participating in the current study reached menopause before the age of 52, Steiner and her colleagues report in the American Journal of Epidemiology. And they found that certain characteristics and exposures appeared to bump up or push back this milestone.

After accounting for factors such as race, education level, family income and participant's smoking status, DES appeared to have the strongest effect on the age of menopause. Exposure to the hormone mimicker sped up the point at which a woman lost her last eggs by about a year. Decades ago, DES was prescribed to pregnant women with the thought that it would reduce the risk of miscarriage and nausea.

Being born at a low birth weight and whether or not a mother had diabetes prior to pregnancy were weakly linked to an earlier arrival of menopause of less than a year.

If a mother gave birth to a girl at the age of 35 or older, the researchers found a hint that menopause might be slightly delayed for that girl.

The researchers note that other factors may explain some of these differences. An older mother, for example, may simply pass down her ability to conceive at a later age - reflective of a later onset of menopause.

"But the point is not one exposure or another," said Steiner. "It's more the idea that the rate we progress to the end of our reproductive life - from puberty and ability to conceive to inability to conceive and menopause - can be changed by such early events."

What are your thoughts on menopause being linked to birth?

Read Parent24’s Comments Policy publishes all comments posted on articles provided that they adhere to our Comments Policy. Should you wish to report a comment for editorial review, please do so by clicking the 'Report Comment' button to the right of each comment.

Comment on this story
Comments have been closed for this article.


Want to know what your baby looks like and what you can expect at this stage?




Play creatively

Don’t let your little one’s frustration with wanting to ‘get things just right’ stop them from playing creatively.

See more >


Everything from parties to pre-schools in your area.